Słowa kluczowe
aktywność biologiczna witaminy K
izomeria geometryczna
Abstrakt
Chinony i ich pochodne (witamina K) są dobrze znanymi cząsteczkami w medycynie. W niniejszym artykule przedstawiono strukturę chemiczną, izomerię konfiguracyjną witaminy K i różnice w aktywności biologiczne jej izomerów.
Bibliografia
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Sitkowski J., Bocian W., Szterk A.: The application of multidimensional NMR analysis to cis/trans isomers study of menaquinone-7 (vitamin K2MK-7), identifi-cation of the (E,Z3,E2,ω)-menaquinone-7 isomer in dietary supplements, Journal of Molecular Structure, Volume 1171, 2018, Pages 449-457, ISSN 0022-2860, https://doi.org/10.1016/j.molstruc.2018.06.029.
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Lal N., Berenjian A.: Cis and trans isomers of the vitamin menaquinone-7: which one is biologically significant? Appl Microbiol Biotechnol. 2020 Apr;104(7):2765-2776. doi: 10.1007/s00253-020-10409-1. Epub 2020 Feb 3. PMID: 32009201.
Baj A., Witkowski S.: Witamina K2 (MK-7) – struktura, aktywność, synteza, Wi-taminy i inne substancje aktywne – przegląd i badania, TYGIEL Lublin 2018 (7 – 18) https://www.researchgate.net/profile/Anna-Piotrowska-10/publication/325253507_Neuropsychiatric_side_effects_of_vitamin_A_derivatives_used_in_dermatological_treatment/links/5b3493c3a6fdcc8506d71e22/Neuropsychiatric-side-effects-of-vitamin-A-derivatives-used-in-dermatological-treatment.pdf
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https://www.marketresearchfuture.com/reports/vitamin-k2-market-7495?utm.
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